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Updated: Aug 12, 2026

Thermodynamics of Membrane Protein Folding Measured by Fluorescence Spectroscopy
Published on: April 28, 2011
Using protein folding rates to test protein folding theories
Blake Gillespie1, Kevin W Plaxco
1Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, California 93106, USA. blakeg@chem.ucsb.edu
Abstract:
The fastest simple, kinetically two-state protein folds a million times more rapidly than the slowest. Here we review many recent theories of protein folding kinetics in terms of their ability to qualitatively rationalize, if not quantitatively predict, this fundamental experimental observation.
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