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A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
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Thromboembolic disease in pregnancy

Nora M Doyle1, Manju Monga

  • 1Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Texas Health Science Center at Houston, 6431 Fannin Street, Houston, TX 77030, USA. nora.m.doyle@uth.tmc.edu

Obstetrics and Gynecology Clinics of North America
|June 18, 2004
PubMed

Venous thromboembolic disease is a major cause of maternal morbidity and mortality. Virchow's triad of hypercoagulability, venous stasis, and vascular damage all occur during pregnancy. The risk of venous thromboembolism is five to six times higher during pregnancy and the puerperium. Risk factors include age greater than 35, antiphospholipid antibodies, inherited thrombophilias, operative delivery, increased parity, obesity, mechanical heart valves,and family history. Prophylactic and therapeutic anticoagulation is recommended for women at risk. Low molecular weight heparins are safe and effective in most cases.

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