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Imaging of Cell Shape Alteration and Cell Movement in Drosophila Gastrulation Using DE-cadherin Reporter Transgenic Flies
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Drosophila gastrulation: identification of a missing link

Maria Leptin1, Markus Affolter

  • 1Institute of Genetics, University of Cologne, Weyertal 121, D-50931 Cologne, Germany. mleptin@uni-koeln.de

Current Biology : CB
|June 19, 2004
PubMed

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Gastrulation01:56

Gastrulation

Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata will form...