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Updated: Aug 23, 2026

In Vitro Multiparametric Cellular Analysis by Micro Organic Charge-modulated Field-effect Transistor Arrays
Published on: September 20, 2021
The demonstration of an enhanced microelectrochemical transistor for measurements in neutral solution at low analyte
1School of Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ, UK.
Abstract:
We report a new, sensitive detection method for the measurement of analytes based on the combination of conducting polymer technology and redox enzyme electrochemistry. This method provides a simple measurement method potentially enabling point of care testing on disposable electrodes in under 60 s. The measurement does not require a reference or counter electrode and the analytical signal is recorded by an ammeter measuring milliampere currents through a polymer transistor. Even at very low analyte concentration, the signal is not subject to significant noise.
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