Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Left ventricular reconstruction: Early and late results.

Lynda L Mickleborough1, Naeem Merchant, Joan Ivanov

  • 1University of Toronto, Ontario, Canada. l.mickleborough@on.aibn.com

The Journal of Thoracic and Cardiovascular Surgery
|June 30, 2004
PubMed
Summary

Left ventricular reconstruction improves outcomes for patients with coronary disease and poor heart function. This surgical option offers good symptom control, excellent survival, and freedom from sudden death.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence and Significance of Pancreatic Iron in Transfusion-Dependent Sickle Cell Disease.

Pediatric blood & cancer·2025
Same author

Transfusional hemosiderosis in childhood cancer patients and survivors.

Pediatric blood & cancer·2024
Same author

Significant pituitary siderosis is common in transfusion-dependent sickle cell disease.

Blood·2024
Same author

Natural History of Myocardial Injury After COVID-19 Vaccine-Associated Myocarditis.

The Canadian journal of cardiology·2022
Same author

Stress Perfusion Cardiac Magnetic Resonance Imaging With a 3.0-Tesla Scanner for Myocardial Viability in a Patient With a Conditional Pacemaker.

CJC open·2022
Same author

We Can Dance If We Want To (with Safety Measures).

mBio·2022

Area of Science:

  • Cardiovascular Surgery
  • Cardiac Reconstruction
  • Heart Failure Management

Background:

  • Coronary artery disease frequently leads to impaired left ventricular function.
  • Ventricular reconstruction is a surgical consideration for patients with akinetic or dyskinetic segments and wall thinning.
  • Optimal patient selection and surgical techniques for ventricular reconstruction remain areas of investigation.

Purpose of the Study:

  • To evaluate the outcomes of ventricular reconstruction in patients with coronary disease and poor left ventricular function.
  • To assess the efficacy of ventricular reconstruction using wall thinning as a primary selection criterion.

Main Methods:

  • Prospective data collection from 285 patients undergoing ventricular reconstruction.
  • Surgical techniques included modified linear closure, septoplasty, and coronary artery bypass grafting.

Related Experiment Videos

  • Concomitant procedures involved ablation for ventricular tachycardia and mitral valve interventions.
  • Main Results:

    • Low operative mortality (2.8%) with significant perioperative support.
    • Mean follow-up of 63 months demonstrated good long-term survival (92% at 1 year, 62% at 10 years).
    • Symptom improvement (67%) and increased ejection fraction (average 10% increase) were observed postoperatively.

    Conclusions:

    • Ventricular reconstruction, guided by wall thinning criteria, is a viable option for selected patients.
    • The procedure offers low operative risk, effective symptom management, and favorable long-term survival.
    • This approach should be considered for patients with coronary disease, reduced ejection fraction, and ventricular wall thinning.