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Related Experiment Videos

Ergogenic aids: human growth hormone.

Jason J Stacy1, Thomas R Terrell, Thomas D Armsey

  • 1Palmetto Health Richland, 3209 Colonial Drive, USC School of Medicine, Columbia, SC 29203, USA.

Current Sports Medicine Reports
|July 3, 2004
PubMed
Summary

Human growth hormone (GH) is medically used but popular with athletes as an ergogenic aid. Despite limited evidence, GH is reputed to enhance athletic performance, leading to detection efforts.

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Area of Science:

  • Endocrinology
  • Sports Medicine
  • Pharmacology

Background:

  • Human growth hormone (GH) has established medical applications.
  • GH is increasingly misused by athletes as an ergogenic aid for performance enhancement.
  • The use of GH and anabolic steroids in sports is a significant concern for athletes, parents, and policymakers.

Purpose of the Study:

  • To review the physiology and medical uses of GH.
  • To assess the efficacy of GH as an ergogenic aid in athletic performance.
  • To discuss the development of methods for detecting illicit GH use in sports.

Main Methods:

  • Literature review of GH physiology, medical indications, and ergogenic effects.
  • Analysis of scientific studies on GH's impact on exercise performance and work capacity.

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  • Overview of current and developing techniques for detecting GH doping.

    • Main Results:

    • Supraphysiologic doses of GH can induce lipolysis and increase muscle volume.
    • Scientific literature provides limited compelling evidence for GH's efficacy as an ergogenic aid due to ethical study limitations.
    • Isolated studies suggest potential for improved athletic performance and anti-aging effects.

    Conclusions:

    • GH has a reputation among athletes for performance enhancement despite insufficient scientific validation.
    • International efforts are underway to detect illegal GH doping, with promising techniques emerging.
    • Further research is needed to clarify GH's true ergogenic potential and risks.