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Updated: Aug 23, 2026

An Orthotopic Mouse Model of Spontaneous Breast Cancer Metastasis
Published on: August 14, 2016
Spontaneous tumors of small mammals
1Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, 2407 River Drive, Knoxville, TN 37955, USA. cgreenac@utk.edu
Abstract:
The most common tumor of guinea pigs is bronchogenic papillary adenoma; of hedgehogs is mammary gland adenocarcinoma; of hamsters is adrenal cortical adenoma; of gerbils is ovarian granulosa cell and theca cell tumors; of mice is pulmonary carcinoma; and of rats is mammary fibroadenoma. A relatively low incidence of tumors is described for chinchillas and hamsters, whereas the incidence of tumors is high for gerbils, hedgehogs, mice, and rats. Limited literature regarding neoplasia exists for prairie dogs, sugar gliders, and chinchillas.

