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Updated: Aug 15, 2026

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
Published on: November 4, 2015
Chronic thromboembolic pulmonary hypertension
William R Auger1, Kim M Kerr, Nick H S Kim
1Division of Pulmonary and Critical Care Medicine, University of California, San Diego, 9300 Campus Point Drive, La Jolla, CA 92037, USA. bauger@UCSD.edu
Insights
Chronic thromboembolic pulmonary hypertension (CTEPH) surgery is increasingly common. This review covers CTEPH diagnosis, surgical evaluation, and outcomes, including the pulmonary thromboendarterectomy procedure.
Area of Science:
- Cardiology
- Pulmonary Medicine
- Surgical Procedures
Background:
- Increasing incidence of chronic thromboembolic pulmonary hypertension (CTEPH) over the past two decades.
- Growth in specialized global programs for CTEPH diagnosis and management.
- Need for comprehensive understanding of CTEPH natural history and treatment.
Purpose of the Study:
- To discuss the natural history and clinical presentation of CTEPH.
- To outline the evaluation process for pulmonary thromboendarterectomy (PTE).
- To review surgical outcomes and the PTE procedure at a specific institution.
Main Methods:
- Review of the natural history and clinical manifestations of CTEPH.
- Description of patient evaluation protocols for PTE.
- Analysis of surgical outcomes and procedural details of PTE.
- Case review of PTE performed at the University of California, San Diego.
Main Results:
- The article details the progression and symptoms associated with CTEPH.
- It elaborates on the criteria and methods for selecting patients for PTE.
- Outcomes data following PTE are presented, highlighting surgical success and recovery.
- A specific institutional experience with the PTE procedure is shared.
Conclusions:
- Surgical intervention, specifically PTE, is a viable and increasingly utilized treatment for CTEPH.
- Careful patient selection and procedural expertise are crucial for favorable outcomes.
- The rise in CTEPH surgery reflects advancements in diagnosis and treatment strategies.
Abstract:
During the past 2 decades, there has been a steady rise in the number of patients with chronic thromboembolic pulmonary hypertension (CTEPH) undergoing surgery and in the number of programs worldwide dedicated to the diagnosis and management of this patient population. This article discusses the natural history and clinical presentation of CTEPH, the evaluation of patients for pulmonary thromboendarterectomy, and the outcomes following surgery, along with a brief review of the procedure as performed at the University of California, San Diego.
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