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Sarcoidosis in Turkey: 1954-2000.
Ozlem Ural Gurkan1, Gokhan Celik, Ozlem Kumbasar
1Department of Chest Medicine, Faculty of Medicine, University of Ankara, Ankara, Turkey.
Annals of Saudi Medicine
|August 18, 2004
Summary
This study compiles 46 years of sarcoidosis data in Turkey, revealing a higher prevalence in females. Further research is needed to understand the disease's incidence and geographical distribution in the country.
Area of Science:
- Pulmonary Medicine
- Rheumatology
- Immunology
Background:
- Sarcoidosis is a multisystemic disease with unknown causes.
- Organ involvement varies by race, location, and gender.
- Diagnosis can be challenging due to its varied presentation.
Purpose of the Study:
- To compile and analyze epidemiological data on sarcoidosis in Turkey from 1954 to 2000.
- To understand the demographic and clinical features of sarcoidosis in the Turkish population.
Main Methods:
- A comprehensive literature review of sarcoidosis case series in Turkey.
- Data extraction from 29 reports published between 1954 and 2000.
- Inclusion of case series with 5 or more patients.
Main Results:
- Data from 1327 sarcoidosis patients were analyzed.
- Females were nearly twice as likely to be diagnosed with sarcoidosis compared to males.
- Common manifestations included erythema nodosum (137 patients) and peripheral lymph node enlargement (119 patients).
- Elevated serum angiotensin-converting enzyme (ACE) levels were observed in 52% of patients.
- Bronchoscopic biopsy emerged as a preferred diagnostic method in recent studies.
Conclusions:
- This study represents the first compilation of 46 years of sarcoidosis data in Turkey.
- Limitations exist, necessitating further research.
- Future studies should focus on the geographical distribution, incidence, and prevalence of sarcoidosis in Turkey.