Related Experiment Videos
Engineering of non-natural receptors
Pascale Mathonet1, Jacques Fastrez
1Laboratoire de Biochimie Physique et des Biopolymères, Institut des Sciences de la Vie, place Louis Pasteur 1, B1348 Louvain-la-Neuve, Belgium.
Current Opinion in Structural Biology
|August 18, 2004
Abstract:
Rational design, usually guided by computational prediction, and selection from libraries of variants of natural proteins have been used with success in the engineering of novel non-natural receptors. Many of these engineered protein binders will find use in biotechnological, diagnostic and medical applications, sometimes in the place of natural antibodies.