Emerging gram-positive bacterial infections

Sameer Elsayed1, Kevin B Laupland

  • 1Department of Pathology and Laboratory Medicine, University of Calgary, 9, 3535 Research Road NW, Calgary, Alberta T2L 2K8, Canada. sameer.elsayed@cls.ab.ca

Insights

Emerging gram-positive bacterial infections, particularly from Staphylococcus and Streptococcus species, are causing significant human disease and mortality. This review examines key clinical and microbiologic aspects of these important emerging pathogens.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Clinical Medicine

Background:

  • Gram-positive bacteria, including Staphylococcus and Streptococcus species, have increasingly emerged as significant human pathogens.
  • These microbes are associated with novel or rarely seen infectious diseases, particularly in industrialized nations.
  • Many of these infections lead to substantial morbidity and mortality despite treatment.

Purpose of the Study:

  • To review the clinical and microbiologic characteristics of key emerging gram-positive bacterial infections.
  • To highlight the significance of Staphylococcus aureus, S. epidermidis, Streptococcus pyogenes, and beta-hemolytic streptococci as emerging pathogens.

Main Methods:

  • This is a review article.
  • Focuses on clinical and microbiologic aspects.
  • Synthesizes information on emerging gram-positive infections.

Main Results:

  • Staphylococcus and Streptococcus species are prominent causes of emerging infectious diseases.
  • Specific species like Staphylococcus aureus, S. epidermidis, and Streptococcus pyogenes are of major concern.
  • These infections present unique clinical challenges and significant health risks.

Conclusions:

  • Emerging gram-positive bacterial infections pose a serious threat to public health.
  • Understanding the clinical and microbiologic features of these pathogens is crucial for effective management.
  • Continued research and surveillance are necessary to combat these evolving infectious diseases.

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