Preeclampsia and eclampsia in parturients from the in vitro fertilization program

Area of Science:

• Reproductive Medicine
• Obstetrics
• Hypertensive Disorders of Pregnancy

Background:

• Women conceiving via in vitro fertilization (IVF) may face elevated risks for pregnancy complications.
• Pregnancy-induced hypertension, including preeclampsia and eclampsia, is a significant concern in obstetric care.

Purpose of the Study:

• To investigate the incidence of preeclampsia and eclampsia in women who conceived through IVF.
• To compare these risks against a control group from the general population.

Main Methods:

• A seven-year retrospective study involving 144 parturients from an IVF program and 39,112 from the general population.
• Analysis focused exclusively on women with singleton pregnancies.
• Statistical comparison using chi-squared tests to determine significant differences in preeclampsia and eclampsia rates.

Main Results:

• Preeclampsia incidence was 2.08% in the IVF group versus 0.40% in the control group (p<0.05).
• Eclampsia occurred in 0.69% of the IVF group and 0.06% of the control group (p>0.10).
• A statistically significant higher risk for preeclampsia was observed in the IVF group.

Conclusions:

• Women conceiving via IVF demonstrate a statistically significantly higher risk for developing preeclampsia.
• The study did not find a statistically significant increased risk for eclampsia in women who conceived via IVF compared to the general population.