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Truncal morbilliform eruption due to nifedipine
1Department of Dermatology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania.
Cutis
|February 1, 1992
Summary
A patient developed a widespread rash after taking nifedipine, a common calcium channel blocker. This case highlights potential skin reactions to this cardiovascular medication.
Area of Science:
- Dermatology
- Pharmacology
- Internal Medicine
Background:
- Nifedipine is a widely prescribed calcium channel blocker used for hypertension and angina.
- Drug-induced dermatologic reactions can range from mild rashes to severe, life-threatening conditions.
Observation:
- A 50-year-old woman presented with a morbilliform eruption affecting her trunk, arms, and legs.
- The facial skin was notably spared from the eruption.
Findings:
- The patient's rash developed subsequent to oral administration of nifedipine.
- This morbilliform eruption represents a potential adverse dermatologic effect of nifedipine therapy.
Implications:
- Clinicians should be aware of the diverse range of skin reactions associated with nifedipine.
- Prompt recognition and management of drug-induced rashes are crucial for patient safety and adherence to treatment.