Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Progestogen therapies: differences in clinical effects?

Inka Wiegratz1, Herbert Kuhl

  • 1Department of Obstetrics and Gynecology, J. W. Goethe University Frankfurt, Frankfurt am Main, Germany.

Trends in Endocrinology and Metabolism: TEM
|September 11, 2004
PubMed
Summary

Estrogen/progestogen preparations offer relief for estrogen-deficiency symptoms. However, progestogens can modify estrogen

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comments on: 'Critical assessment of a prolonged-release EE/DNG contraceptive safety analysis' - a letter to the editor to the European Jornal of Contraception by Jonathan Douxfils et al.

The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception·2026
Same author

One-year clinical experience on the thromboembolic safety profile of the first prolonged release combined oral contraceptive containing 2 mg dienogest and 0.02 mg ethinyl-oestradiol.

The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception·2025
Same author

Heavy Menstrual Bleeding in Women Treated with Direct Oral Anticoagulants: Results of the Prospective HEMBLED Registry.

Thrombosis and haemostasis·2025
Same author

The risk of thromboembolism and use of combined oral contraceptives: a comment.

BJOG : an international journal of obstetrics and gynaecology·2023
Same author

The drospirenone (DRSP)-only pill: clinical implications in the daily use.

The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception·2023
Same author

Correction: Oral Progestins in Hormonal Contraception: Importance and Future Perspectives of a New Progestin Only-Pill Containing 4 mg Drospirenone.

Geburtshilfe und Frauenheilkunde·2022

Area of Science:

  • Endocrinology
  • Pharmacology

Background:

  • Numerous estrogen/progestogen preparations exist for estrogen-deficiency symptoms.
  • These therapies vary in administration route, estrogen type/dose, and progestogen type/dose.

Purpose of the Study:

  • To review the modulating effects of various progestogens on estrogen therapy.
  • To highlight the impact of progestogen chemical structure on treatment outcomes.

Main Methods:

  • Literature review of clinical and epidemiological data.
  • Analysis of progestogen hormonal patterns and their effects.

Main Results:

  • Progestogens are indicated solely for endometrial protection.
  • Depending on structure, progestogens can enhance or antagonize estrogen's effects on various systems (e.g., hot flushes, bone density, mood, lipid metabolism).
  • Progestogens possess diverse hormonal activities beyond progestogenic and antiestrogenic actions.

Conclusions:

  • Direct comparative trials on progestogen effects are lacking.
  • Clinical data are insufficient to definitively conclude the clinical relevance of differences among progestogens.

Related Experiment Videos