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Updated: Aug 22, 2026

Profiling of Surface Protein Epitopes on Viral Particles by Multiplex Dual-Reporter Strategy
Published on: January 12, 2024
Comparison of multiplexed techniques for detection of bacterial and viral proteins
Rupa S Rao1, Steven R Visuri, Mary T McBride
1Lawrence Livermore National Laboratory, Livermore, California 94550, USA.
Abstract:
Immobilized antibody microarrays were compared to the Luminex flow cytometry system that utilizes suspensions of polystyrene microbeads covalently coupled with capture antibodies. The two immunoassays were performed for comparison of reproducibility, limits of detection and dynamic range. The Luminex system showed lower limits of detection and increased dynamic range among samples whereas the protein microarrays could be more amenable to miniaturization. Both technologies were capable of sensitive multiplexed detection.
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