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Related Experiment Videos

RDP2: recombination detection and analysis from sequence alignments.

D P Martin1, C Williamson, D Posada

  • 1Institute of Infectious Diseases and Molecular Medicine, University of Cape Town Cape Town 7000, South Africa. darren@science.uct.ac.za

Bioinformatics (Oxford, England)
|September 21, 2004
PubMed
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RDP2 is a software tool that identifies recombinant sequences and breakpoints in nucleotide alignments using 10 methods. It offers automated analysis for large datasets and interactive result verification.

Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genetics

Background:

  • RDP2 is a freely available software for Windows.
  • It implements 10 established recombination detection methods.
  • The program is accessible via its official website.

Purpose of the Study:

  • To introduce RDP2, a program for detecting recombination in nucleotide sequences.
  • To provide a tool for automated and interactive analysis of sequence alignments.

Main Methods:

  • Utilizes 10 published recombination detection methods (e.g., GENECONV, BOOTSCAN).
  • Analyzes nucleotide sequence alignments.
  • Supports interactive exploration and verification of results.

Main Results:

Related Experiment Videos

  • Identifies recombinant sequences and recombination breakpoints.
  • Enables fast, automated analysis of large alignments (up to 300 sequences, 13,000 sites).
  • Facilitates interactive management and verification of detected recombination events.

Conclusions:

  • RDP2 offers a comprehensive solution for recombination detection in sequence data.
  • The software supports both automated and interactive analysis workflows.
  • It aids researchers in understanding genetic recombination events.