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High protein mobility in skinned rabbit muscle fibres observed by 1H NMR spectroscopy
H R Kalbitzer1, M Schrumpf, J Wray
1Max-Planck-Institute for Medical Research, Department of Biophysics, Heidelberg, Germany.
FEBS Letters
|February 24, 1992
Abstract:
1H NMR spectra of skinned rabbit muscle fibers show a group of relatively sharp resonance lines which presumably originate from highly mobile protein domains. Comparison with the spectrum of myosin subfragment 1 suggests that these signals may come at least partly from mobile regions of the myosin head. NMR could possibly be used to characterize the movements of crossbridges in force generation.