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Ocular pseudoexfoliation associated with hearing loss
Reham I Shaban1, Wafa M Asfour
1Department of Ophthalmology, Royal Jordanian Medical Services, King Hussein Medical Center, Amman, Jordan.
Saudi Medical Journal
|September 28, 2004
Summary
Ocular pseudoexfoliation (PXF) is linked to sensorineural hearing loss. This study found most PXF patients had poorer hearing than controls, suggesting PXF is a systemic condition.
Area of Science:
- Ophthalmology
- Audiology
- Systemic Diseases
Background:
- Ocular pseudoexfoliation (PXF) is increasingly recognized as a systemic condition.
- Evidence suggests PXF may affect organs beyond the eye.
Purpose of the Study:
- To investigate the association between ocular pseudoexfoliation (PXF) and sensorineural hearing loss.
- To compare hearing thresholds in PXF patients with age-matched controls.
Main Methods:
- Prospective study of 41 patients with ocular PXF.
- Pure tone hearing threshold measurements at 1, 2, and 3 kHz.
- Comparison with International Standard (ISO 7029) median age-associated hearing loss (AAHL).
Main Results:
- 87% of PXF patients exhibited elevated hearing threshold levels (HTL) compared to AAHL.
- No significant correlation was found between glaucoma and sensorineural hearing loss.
- The majority of patients demonstrated sensorineural hearing loss.
Conclusions:
- A high prevalence of sensorineural hearing loss exists in patients with ocular PXF.
- These findings support the concept of PXF as a systemic disease.
- Further research into PXF's systemic manifestations is warranted.
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