[Rhabdomyosarcoma of the breast in girls]

Cases of rhabdomyosarcoma (RMS) in 14 year old girls are described. The tumor was very aggressive with early and widespread metastases in regional and other lymph nodes, soft tissues, various parts of the skeleton, bone marrow, lungs. The diagnosis and spread of this tumour was established on the basis of total examination of the girls. Clinical stage III was found in one girl, stage IV in two patients with RMS of the breast. Diagnoses were confirmed histologically (open biopsy of the tumours). Bilateral alveolar RMS of the breast (synchronic or metachronic) was diagnosed in all the patients. Light and electron microscopies were insufficient for final diagnosis, histogenesis of the tumour was established by means of immunohistochemistry. All the patients died within 3 months to one year and half after diagnosis.