Psoriasis: future research needs and goals for the twenty-first century

Psoriasis research is entering a new era. Progress in delineating immunogenetics and pathomechanisms of disease brings with it a need to understand fully the clinical spectrum of disease and integrate phenotype with genomics and proteomics. Involvement of patient groups and an understanding of the psychosocial aspects of psoriasis, particularly its significant impairment of quality of life, are keys to progress. The biologic revolution in therapy of inflammatory disease has embraced psoriasis bringing with it an urgent need for evidence-base, consensus on outcome measures, and long-term real-life studies.A concerted effort between academia, industry, and patients will take forward the understanding of, and therapy for, psoriasis.