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[Multiple sclerosis with sensory disturbances and hyperhidrosis of the hand]

V Deramecourt1, J De Seze, S Delalande

  • 1Service de Neurologie D, Hôpital R. Salengro, CHRU, Lille.

Revue Neurologique
|September 30, 2004
PubMed
Abstract

Insights

Focal hyperhidrosis, a rare symptom of excessive sweating, can indicate underlying neurological conditions. This case highlights focal hyperhidrosis as an early indicator of multiple sclerosis.

Area of Science:

  • Neurology
  • Autonomic Nervous System Disorders
  • Neuroimmunology

Background:

  • Hyperhidrosis can stem from central or peripheral nervous system damage.
  • Autonomic dysfunction is a known complication in advanced multiple sclerosis.

Observation:

  • A 26-year-old patient presented with sensory disturbances and localized excessive sweating of the right hand.
  • Magnetic resonance imaging (MRI) identified demyelinating lesions, including one in the pons enhancing with gadolinium.
  • Cerebrospinal fluid analysis revealed oligoclonal IgG bands, supporting the diagnosis.

Findings:

  • The patient's focal hyperhidrosis was attributed to a lesion affecting the crossed sympathetic inhibitory tract.
  • This presentation suggests focal hyperhidrosis can be an initial manifestation of multiple sclerosis.

Implications:

  • Focal hyperhidrosis may serve as an early diagnostic clue for multiple sclerosis.
  • Understanding this association can improve early diagnosis and management of multiple sclerosis patients with autonomic symptoms.

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