Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diffusion systems for evaluation of biomineralization.

L Silverman1, A L Boskey

  • 1Yeshiva University, 500 West 185 St., New York, NY 10033, USA.

Calcified Tissue International
|September 30, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Minimal residual disease and outcome characteristics in infant KMT2A-germline acute lymphoblastic leukaemia treated on the Interfant-06 protocol.

European journal of cancer (Oxford, England : 1990)·2021
Same author

Outcome of relapsed infant acute lymphoblastic leukemia treated on the interfant-99 protocol.

Leukemia·2017
Same author

Insights into the bisphosphonate holiday: a preliminary FTIRI study.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2017
Same author

Outcome of relapsed infant acute lymphoblastic leukemia treated on the interfant-99 protocol.

Leukemia·2015
Same author

Epigenetic and molecular signatures of cord blood CD34(+) cells treated with histone deacetylase inhibitors.

Vox sanguinis·2015
Same author

Vibrational spectroscopic imaging for the evaluation of matrix and mineral chemistry.

Current osteoporosis reports·2014

Gel diffusion methods effectively study matrix molecules in biomineralization. These techniques use minimal material and can assess modified molecules and synthetic analogs for biomineralization mechanisms.

Area of Science:

  • Biochemistry
  • Materials Science
  • Biomineralization Research

Background:

  • Matrix molecules play crucial roles in biomineralization.
  • In vitro study methods are essential for understanding these roles.
  • Gel diffusion-precipitation offers a unique approach to studying mineralization.

Purpose of the Study:

  • To review the advantages and limitations of gel diffusion-precipitation methods for studying biomineralization.
  • To highlight the utility of these methods for characterizing matrix molecule effects.
  • To discuss the application of gel methods as a mineralization assay system.

Main Methods:

  • Gel diffusion-precipitation techniques.
  • In vitro biomineralization assays.
  • Characterization of matrix molecules (gelatin, agar, agarose) and synthetic analogues.

Related Experiment Videos

Main Results:

  • Gel diffusion methods are effective for elucidating matrix molecule roles in biomineralization.
  • These methods require only small quantities of material.
  • Gel methods can be adapted as mineralization assays for modified molecules and synthetic analogs.

Conclusions:

  • Gel diffusion-precipitation is a valuable tool for biomineralization research.
  • The versatility of gel methods allows for the study of various matrix molecules and their effects.
  • Further exploration of gelatin, agar, agarose, and other gel systems can advance understanding of biomineralization mechanisms.