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Published on: March 6, 2019
Synthesis of new diselenide compounds as anti-inflammatory agents
Liulan Shen1, Kyung-Min Shin, Kyung-Tae Lee
1College of Pharmacy, Kyung Hee University, Seoul 130-701, Korea.
Abstract:
Many diselenide compounds are used as antioxidants, enzyme inhibitors and cytokine inducers. Three new diselenide compounds, bis-(2-hydroxyphenyl) diselenide, bis-(3-hydroxyphenyl) diselenide and bis-(4-hydroxyphenyl) diselenide were designed and synthesized as anti-inflammatory agent. All of them were found to have strong in vitro activity in anti-inflammatory assays.
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