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Updated: Aug 21, 2026

Robotic-assisted Bronchoscopy Combined with Multimodal Imaging for Targeted Lung Cryobiopsies
Published on: July 19, 2024
A case of early-stage lung cancer detected by autofluorescence bronchoscopy
Masaki Hanibuchi1, Seiji Yano, Nobutaka Edakuni
1Department of Internal Medicine and Molecular Therapeutics, Course of Bioregulation and Medical Oncology, The University of Tokushima School of Medicine, Tokushima, Japan.
Abstract:
A 71-year-old man was referred to our hospital for further examination of abnormal sputum cytology. No abnormal nodular shadows were detected in chest X-ray and chest CT. The location of the tumor was clearly identified as a defect of autofluorescence by autofluorescence bronchoscopy at the bifurcation between the left B1+2 and B3 bronchi, whereas it was quite difficult by conventional bronchoscopy. Transbronchial biopsy revealed squamous cell carcinoma. Further examinations yielded the diagnosis of early-stage lung cancer. Photodynamic therapy was performed and complete response was confirmed. This case indicates the efficacy of autofluorescence bronchoscopy for detecting early-stage lung cancer.
