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Epidermal growth factor receptor in tumor angiogenesis
1The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Box 444, Houston, TX 77030-4009, USA. lellis@mail.mdanderson.org
Hematology/Oncology Clinics of North America
|October 12, 2004
Abstract:
This article focuses on the preclinical evidence for activation of the epidermal growth factor receptor (EGFR) in promoting angiogenesis and the efficacy of anti-EGFR agents in inhibiting angiogenesis and tumor growth.