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Evaluation of antitussive activity of Lagerstroemia parviflora leaf extract
Avijit Mazumder1, B P Saha, S P Basu
1Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi, India. avijitmazum@yahoo.com
Phytotherapy Research : PTR
|October 13, 2004
Abstract:
The methanol extract of the leaves of Lagerstroemia parviflora Roxb was investigated for its effect on a cough model induced by sulfur dioxide gas in mice. It exhibited significant antitussive activity when compared with the control in a dose-dependent manner. The L. parviflora extract (100, 200, 300 mg/kg) showed maximum inhibition of cough reflex at 90 min after drug administration and the antitussive activity was comparable to that of codeine phosphate, a standard antitussive agent.