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Updated: Aug 21, 2026

A Workflow to Quantitatively Determine Age-Related Macular Degeneration Lesion-Specific Variations in Fundus Autofluorescence
Published on: May 26, 2023
A novel high-resolution kinetic method for visual field mapping of scotoma in age-related macular degeneration
Dror Zur1, Guy J Ben Simon, Anat Loewenstein
1Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel.
Background And Objective:
To examine a new high-resolution kinetic mapping method for scotoma in age-related macular degeneration.
Patients And Methods:
A computer-based program for kinetic visual field mapping was tested in 10 healthy subjects and 14 patients with age-related macular degeneration and fixed preferred retinal locus. The stimulus was presented using a back projector on a screen located 40 cm from the subject. The findings were then compared with static results.
Results:
Control group mapping revealed good congruency with the anatomic blind spot. Mapping of the 14 patients with age-related macular degeneration was rapid and revealed good accuracy. The average deviation of the mapping border from the anatomic scotoma border was no more than 3.1% of the scotoma radius. Static mapping of 7 of the patients with age-related macular degeneration was longer and revealed lower accuracy.
Conclusions:
The proposed method is more rapid, accurate, and consistent than static mapping. It allows accurate mapping of central scotoma with suprathreshold stimulus, and may be used in the future for detecting the early stages of age-related macular degeneration using subthreshold stimulus.

