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Updated: May 2, 2026

Inducement and Evaluation of a Murine Model of Experimental Myopia
Published on: January 22, 2019
[The image futures of optical coherence tomography in pathologic myopia]
Guang-lu Wang1, Ming-yang Wang, Ying Xiong
1Beijing Tongren Ophthalmic Center, Capital University of Medical Sciences, Beijing 100730, China. continent23@163.com
Objective:
To study the characteristics of optical coherence tomography (OCT) pictures in pathologic myopia.
Methods:
100 cases (195 eyes) of pathologic myopia were examined with OCT. The Age ranges of all the cases was 16-76 years and refraction error was -6.00 - -36.00 diopters.
Results:
OCT image was normal in 7 eyes (4.3%), the reflectivity band of RPE and chorio-capillaries were uneven and thinning in 147 eyes (90.2%). Full-thickness macular hole was found in 21 eyes (10.8%), of which 10 (5.1%) eyes were associated with retinal detachment; local shallow retinal detachment was found in 24 eyes (12.3%), of which 7 eyes (3.6%) were associated with retinal schisis, 19 eyes (9.7%) with macular choroidal neovascularization (CNV). retinal swelling was often associated with the following diseases: Fuchs spot 9 eyes (4.6%), thick macular hemorrhage 3 eyes, epiretinal macular membrane 18 eyes (9.2%); macular sensory retina thinning in 5 eyes (2.6%).
Conclusion:
Compared with fundus examination including slit lamp with pan-retinoscope, OCT showed unique preference for observation of the changes of retinal pigment epithelium (RPE), chorio-capillary layer, diagnosis macular hole and epiretinal macular membrane, discovery of small sensory retinal detachment, schisis and thinning of sensory retina layer etc. OCT can not either discover a piece of thin macular hemorrhage or differentiation between thick macular hemorrhage and pigment spot.
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