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Quantitative Measurement of γ-Secretase-mediated Amyloid Precursor Protein and Notch Cleavage in Cell-based Luciferase Reporter Assay Platforms
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gamma-Secretase as a target for drug intervention in Alzheimer's disease

Timothy Harrison1, Ian Churcher, Dirk Beher

  • 1Merck Sharp & Dohme Research Laboratories, The Neuroscience Research Centre, Terlings Park, Harlow Essex CM20 2QR, UK. timothy_harrison@merck.com

Current Opinion in Drug Discovery & Development
|October 27, 2004
PubMed

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