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Published on: March 8, 2019
Intraocular lens exchange for late-onset opacification
J van Looveren1, M J Tassignon
1Department of Ophthalmology, University of Antwerp, Belgium. oftalmo@uia.ua.ac.be
Bulletin De La Societe Belge D'Ophtalmologie
|October 30, 2004
Summary
Late opacification of Hydroview intraocular lenses (IOLs) can cause significant vision loss, necessitating explantation. Analysis revealed calcium phosphate deposits as the cause of this Hydroview IOL complication.
Area of Science:
- Ophthalmology
- Biomaterials Science
- Medical Device Analysis
Background:
- Late postoperative opacification of intraocular lenses (IOLs) is a concern.
- Hydroview IOLs have been associated with opacification issues.
Purpose of the Study:
- To analyze Hydroview IOLs explanted due to late opacification.
- To investigate the clinical, microscopic, and spectroscopic characteristics of these opacified IOLs.
Main Methods:
- Retrospective study of secondary lens implantations for Hydroview IOL opacification.
- Gross, light microscopic, and RAMAN spectroscopic evaluation of explanted IOLs.
Main Results:
- Seven eyes (six patients) required lens exchange for Hydroview IOL opacification between 15-25 months post-implantation.
- Opacification, primarily in the anterior optic, consisted of calcium phosphate deposits.
- Visual acuity improved post-explantation in most cases.
Conclusions:
- Late Hydroview IOL opacification can lead to severe visual impairment and requires explantation.
- Calcium phosphate is implicated in the opacification process.
- Reporting such medical device complications is mandatory.
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