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Updated: Aug 21, 2026
Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice
Published on: May 10, 2019
[Investigation on the frequency specificity of the auditory brainstem response to tone burst in three different
Shili Wang1, Xueming Chen, Yan fen Ye
1Department of Otolaryngology, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025.
Objective:
This study investigated and compared the effects of tone burst in three different conditions (linear-gated tone burst, linear-gated tone burst in broadband noise masking and Blackman-gated tone burst) on the frequency specificity of ABR.
Method:
The latencies of ABR wave V were recorded respectively on sixteen normal-hearing adults using 1, 2 and 4 kHz tone bursts in three types of stimuli at different intensities.
Result & Conclusion:
1. Three types of tone bursts may evoke similar frequency-specific ABR when stimulus intensity was lower than 70 dB nHL for 1 kHz and any intensity for 2, 4 kHz. At the high-intensity(> or = 70 dB nHL) for lower frequency (1 kHz), however, linear-gated tone burst had poor frequency specificity due to the increased effects of spectral splatter. To improve the frequency specificity, linear-gated tone burst should be mixed with masking noise or using Blackman-gated tone burst directly. 2. Both linear-gated tone burst in broadband noise masking and Blackman-gated tone burst of 1 kHz, 2 kHz and 4 kHz at any intensity can produce frequency-specific ABR, but response amplitudes were smaller for the broadband noise masking condition than for the Blackman-gated one. Therefore the Blackman-gated tone burst is prefered.
