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ACAP1 promotes endocytic recycling by recognizing recycling sorting signals.

Jun Dai1, Jian Li, Erik Bos

  • 1Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.

Developmental Cell
|November 5, 2004
PubMed
Summary

ACAP1 directly binds recycling cargo proteins, promoting their sorting in endocytic pathways. This interaction is crucial for transferrin receptor (TfR) recycling, revealing a novel cargo sorting mechanism.

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