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Updated: Aug 21, 2026

The Immediate Partial Removal of Cumulus-Oocyte Complexes: A Refined Approach for Rapid Observation of In Vitro Fertilization
Published on: October 18, 2024
Does seasonality alter intrauterine insemination outcomes: a 5-year study
J Glenn Proctor1, Dawn W Blackhurst, William R Boone
1Department of Obstetrics and Gynecology, Greenville Hospital System, Greenville, South Carolina, USA.
Purpose:
To determine if seasonal changes alter pregnancy rate in intrauterine insemination (IUI) patients.
Methods:
One-thousand and eighty semen analyses prepared for IUI were evaluated in this retrospective cohort study of 496 patients.
Results:
Volume, pH, sperm concentration, and pregnancy rates were not altered by season. However, the percent motility, the total motile spermatozoa in the ejaculate, the straight-line velocity (VSL) of spermatozoa, as well as the morphology of sperm were altered by season. In a subset of these patients that were defined as normal, only the VSL and the morphology of the spermatozoa were altered by seasonal changes.
Conclusions:
Seasonality alters sperm motility parameters as well as morphology, but these changes are not significant enough to alter pregnancy rates.
