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Partial laryngectomy for recurrent glottic carcinoma after radiotherapy
Aniel Sewnaik1, Cees A Meeuwis, Theo H van der Kwast
1Department of Otolaryngology Head and Neck Surgery of the Erasmus Medical Center, Dr. Molenwaterplein 40, 3015 GD Rotterdam, The Netherlands. a.sewnaik@erasmusmc.nl
Head & Neck
|November 6, 2004
Summary
Partial laryngectomy offers a satisfying treatment for selected glottic cancer patients with radiation failure. Techniques like endoscopic laser surgery and frontolateral partial laryngectomy show promise for local control.
Area of Science:
- Otolaryngology
- Surgical Oncology
Background:
- Early laryngeal cancer management involves surgery or radiotherapy.
- Partial laryngectomy is an alternative to total laryngectomy for patients with radiation failure.
Purpose of the Study:
- To evaluate the efficacy of two partial laryngectomy techniques in treating radiation-failure glottic cancer.
- To compare outcomes between endoscopic laser surgery and frontolateral partial laryngectomy.
Main Methods:
- Patients were divided into two groups: endoscopic laser surgery (n=42) and frontolateral partial laryngectomy (n=21).
- Outcomes were assessed based on local control and cure rates.
Main Results:
- Endoscopic CO2 laser treatment achieved cure in 14/24 patients without anterior commissure involvement and 8/18 with anterior commissure involvement.
- Frontolateral partial laryngectomy resulted in local control in 15/21 patients.
Conclusions:
- Partial laryngectomy is a viable and effective treatment for selected glottic cancer patients who have failed radiation therapy.
- Surgeon familiarity with techniques and indications for partial laryngectomy is crucial for successful outcomes.