Related Experiment Video
Updated: Aug 21, 2026

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
Published on: April 12, 2019
Osseous metaplasia: case report and review
Trifon Lainas1, Ioannis Zorzovilis, Georgios Petsas
1Iatriki Erevna-IVF Unit, Athens, Greece.
Objective:
To discuss, through the experience of a case report and extensive literature review, the best practices for the diagnosis and treatment of osseous metaplasia, which is the cause of secondary infertility.
Design:
Case report.
Setting:
In vitro fertilization unit in Athens.
Patient(S):
A 40-year-old woman with a 10-year history of secondary infertility.
Intervention(S):
Hysteroscopic diagnosis and removal of the bony fragment.
Main Outcome Measure(S):
Elimination of secondary infertility caused by osseous metaplasia.
Result(S):
After treatment, the woman underwent an IVF program and a healthy neonate was born with cesarean section.
Conclusion(S):
Hysteroscopy remains the best practice for the diagnosis and removal of endometrial ossifications, causing secondary infertility.
Related Concept Videos
Cellular Adaptation IV: Dysplasia and Metaplasia
Osteoclasts in Bone Remodeling
Bone Remodeling
Bone Formation by Endochondral Ossification
Growth of Cartilage and Bone Tissue

