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Updated: Aug 21, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
Health plans' strategies to control prescription drug spending
Stanley S Wallack1, Dana Beth Weinberg, Cindy Parks Thomas
1Schneider Institute for Health Policy, Heller School for Social Policy and Management, Brandeis University, Waltham, MA, USA. wallack@brandeis.edu
Abstract:
A number of recent studies have documented the sizable impact of consumer cost sharing without accounting for the other drug management strategies being adopted simultaneously. This qualitative case study of five of California's largest health plans examines the strategies and methods used to control prescription drug use and spending. Higher cost sharing is being used increasingly. Concurrently, major administrative efforts directed at physicians-including rules, incentives, and education-are being undertaken. These efforts have focused on lowering the cost per prescription by emphasizing generic substitution and therapeutic interchange of less costly drugs.
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