Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Blue light differentially alters cellular redox properties.

Jill B Lewis1, John C Wataha, Regina L W Messer

  • 1School of Dentistry, Department of Oral Biology & Maxillofacial Pathology, Medical College of Georgia, Augusta, Georgia 30912, USA. jillewis@mail.mcg.edu

Journal of Biomedical Materials Research. Part B, Applied Biomaterials
|November 17, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lithography-defect-driven source-mask optimization solution for full-chip optical proximity correction.

Applied optics·2021
Same author

Release of calcium ions from particulate monosodium titanates for dental mineralization applications.

American journal of dentistry·2019
Same author

Biological effects of Ni(II) on monocytes and macrophages in normal and hyperglycemic environments.

Journal of biomedical materials research. Part A·2018
Same author

Health System Creation and Integration at a Health Sciences University: A Five-Year Follow-up.

Journal of healthcare management / American College of Healthcare Executives·2017
Same author

Cytotoxicity of Titanate-Calcium Complexes to MC3T3 Osteoblast-Like Cells.

BioMed research international·2017
Same author

Zirconia in biomedical applications.

Expert review of medical devices·2016
Same journal

Biomechanical Performance of Zirconia-Calcium Silicate-Silver Hybrid Dental Crown Under Static and Transient Dynamic Loading: A Finite Element and TOPSIS-Based Multi-Criteria Evaluation.

Journal of biomedical materials research. Part B, Applied biomaterials·2026
Same journal

Synthesis, Characterization, and Implantation of Ferulic Acid-Loaded Chitosan/Aloe vera Hydrogels in Rat Full-Thickness Wound Model.

Journal of biomedical materials research. Part B, Applied biomaterials·2026
Same journal

Double-Crosslinked SIS-Derived Collagen/Alginate Hydrogel With Antibacterial and Pro-Regenerative Activities for Soft Tissue Repair.

Journal of biomedical materials research. Part B, Applied biomaterials·2026
Same journal

Silver and Gold Nanoparticles Promote Antimicrobial Activity and Modulate Inflammation in Escherichia coli-Infected Wounds.

Journal of biomedical materials research. Part B, Applied biomaterials·2026
Same journal

Injectable Thermosensitive Placental ECM-Copper Hydrogel With Endothelial Progenitor Cells for Pressure Ulcer Repair.

Journal of biomedical materials research. Part B, Applied biomaterials·2026
Same journal

Strut Thickness and Species-Specific Healing Are Key Considerations in Developing Zinc-Based Biodegradable Arterial Stents.

Journal of biomedical materials research. Part B, Applied biomaterials·2026
See all related articles

Blue light exposure triggers oxidative stress, leading to different outcomes in various cell types. This research explores blue light

Area of Science:

  • Biomedical Optics
  • Cell Biology
  • Photochemistry

Background:

  • Blue light (380-500 nm) has dual roles: initiating biomaterial polymerization and acting as a therapeutic agent.
  • Emerging research indicates blue light elicits cell-type-specific responses mediated by redox changes.

Purpose of the Study:

  • To investigate the effects of defined blue light doses on cellular responses.
  • To determine if blue light induces oxidative stress and cell-type-specific outcomes.

Main Methods:

  • Cultured monocytes, normal epidermal keratinocytes (NHEK), and OSC2 oral tumor cells were exposed to blue light (5 J/cm² and 60 J/cm²).
  • Assessed parameters included viable cell number, protein profiles, succinate dehydrogenase (SDH) activity, reactive oxygen species (ROS) levels, and apoptosis induction.

Related Experiment Videos

Main Results:

  • Blue light inhibited monocyte growth and increased peroxiredoxins.
  • NHEK cells showed slightly enhanced SDH activity, while OSC2 cells exhibited significant SDH suppression.
  • OSC2 cells displayed higher ROS levels and induced apoptosis compared to NHEK cells.

Conclusions:

  • Blue light induces an oxidative stress response in cells.
  • The cellular outcomes of blue light exposure are cell-type-specific, highlighting its potential biological risks and therapeutic applications.