Treatment of subclinical mastitis

Topics addressed in this article include applied pharmacology of the bovine mammary gland, principles of antibiotic sensitivity testing, mechanisms of antimicrobial resistance, causes of treatment failures, diagnostic considerations, and therapy of specific subclinical mastitis syndromes. Recent research concerning systemic therapy of subclinical mastitis is highlighted and critically reviewed. Limitations of antibiotic sensitivity testing are discussed. The lack of proven, efficacious therapy for many subclinical mastitis syndromes is emphasized.