Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Historical evolution of the sentinel lymph node].

Salvatore Vieni1, Stefania Latteri, Calogero Cipolla

  • 1Dipartimento di Discipline Chirurgiche ed Oncologiche, Sezione di Chirurgia Oncologica, Università degli Studi di Palermo.

Chirurgia Italiana
|November 24, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An intriguing journey into the hereditary syndromes predisposing to endometrial cancer: more than believed.

Therapeutic advances in medical oncology·2026
Same author

From Feasibility to Individualization: Surgery for Breast Cancer Liver and Lung Metastases.

Cancers·2026
Same author

Minimally Invasive Hepatic Resection Option for Access to the Waiting List of a Single Regional Transplant Center in Southern Italy: Entry and Dropout Flows' Analysis.

Journal of clinical medicine·2025
Same author

Breast-Conserving Surgery in <i>BRCA</i> Mutation Carriers: A Paradigm Shift Toward Individualized, Multidisciplinary Care.

Life (Basel, Switzerland)·2025
Same author

Cytokines in sepsis: a critical review of the literature on systemic inflammation and multiple organ dysfunction.

Frontiers in immunology·2025
Same author

<i>POLE</i>-mutated endometrial cancer: new perspectives on the horizon?

Frontiers in oncology·2025

Sentinel node biopsy, a reliable technique for cancer staging, accurately identifies the first lymph node affected by metastasis. This method, particularly for early breast cancer, shows promise in replacing traditional axillary dissection for nodal staging.

Area of Science:

  • Oncology
  • Surgical Pathology
  • Medical Imaging

Context:

  • The sentinel lymph node is the initial site for metastasis from a primary tumor.
  • Lymphatic mapping and sentinel node biopsy (SNB) emerged in the late 20th century.
  • Techniques like dye-guided and radio-guided procedures demonstrate high identification and accuracy rates.

Purpose:

  • To review the history and validation of the sentinel node biopsy technique.
  • To highlight the significance of SNB in cancer staging.
  • To discuss the potential of SNB as a replacement for axillary dissection in early breast cancer.

Summary:

  • Sentinel node biopsy involves identifying and removing the first lymph node to which cancer cells are likely to spread.
  • The reliability of SNB is supported by high accuracy rates in identifying metastatic cells.

Related Experiment Videos

  • Intraoperative lymphatic mapping advancements in the 1990s led to widespread acceptance of the sentinel node theory.

    • Impact:

    • Sentinel node biopsy is becoming the preferred nodal staging procedure for early-stage breast cancer.
    • This technique offers a less invasive alternative to complete axillary lymph node dissection.
    • SNB enhances the accuracy of cancer staging, guiding treatment decisions and improving patient outcomes.