Crossing the quality chasm: a requirement for successful cervical cancer prevention in developing countries

Disease prevention requires sociopolitical change, which in turn requires the participation of those for whom the change is intended, including demographic groups at high risk for disease, appropriate governmental authorities, and essential health care personnel. Multiparous women of lowest socioeconomic status, the demographic group at highest risk for the development of cervical cancer, lack sociopolitical leverage almost by definition. Pap screening in developing countries is an idea whose time has come, but it is also an ethical imperative currently lacking a substantial sociopolitical constituency. Noncytologic screening methods currently benefit from sponsorship by corporate manufacturers and by donor organizations such as the Bill and Melinda Gates Foundation. Pap screening efforts in developing countries will benefit from the involvement of cytology organizations based in developed countries. Future assessments of the progress of cervical cancer prevention efforts in developing countries will benefit from additional examination of the interactions between quality and sociopolitical obstacles to change. Many of these obstacles will be elucidated by following the money, as well as the science, involved in cervical screening activities.