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Updated: Aug 20, 2026

Important Endpoints and Proliferative Markers to Assess Small Intestinal Injury and Adaptation using a Mouse Model of Chemotherapy-Induced Mucositis
Published on: May 12, 2019
Oral mucositis
Rajesh V Lalla1, Douglas E Peterson
1Division of Oral Medicine, Department of Oral Diagnosis, University of Connecticut School of Dental Medicine, 263 Farmington Avenue, Farmington, CT 06030, USA. lalla@nso2.uchc.edu
Abstract:
Oral mucositis refers to erythematous, erosive, and ulcerative lesions of the oral mucosa seen in two patient populations: (1) head and neck cancer patients undergoing radiation therapy to fields involving the oral cavity, and (2) patients receiving high-dose chemotherapy for cancer. Oral mucositis is a significant and dose-limiting toxicity of cancer therapy, with important clinical and economic implications. This article reviews the current knowledge on the pathogenesis, clinical presentation, diagnosis, and management of oral mucositis.
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