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Hyperplastic polyps and serrated adenomas: colonoscopic surveillance?
M L C Stellakis1, K M Reddy, A Arnaout
1Colorectal Unit, Mayday University Hospital, 530 London Road, Croydon, London CR7 7YE. mr.stellakis@doctors.org.uk
Summary
Hyperplastic polyps are generally considered benign. However, new evidence suggests a potential pathway from hyperplastic polyps to serrated adenomas, necessitating further investigation and possible surveillance.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Hyperplastic polyps (HPs) are traditionally viewed as non-neoplastic lesions.
- Current clinical practice generally does not involve regular screening for HPs due to their perceived lack of malignant potential.
Observation:
- This report details two cases of serrated adenomas (SAs).
- These cases contribute to a growing body of evidence suggesting a possible transition from hyperplastic polyps to neoplastic lesions.
Findings:
- The findings suggest a potential hyperplastic to neoplastic pathway.
- This pathway may involve the progression of HPs to SAs, challenging the established understanding.
Implications:
- Regular colonoscopic surveillance might be warranted for patients with hyperplastic polyposis.
- Further research is needed to clarify the malignant potential and optimal management of HPs.