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Posttraumatic segmental axial dystonia.

B Jabbari1, J Paul, B Scherokman

  • 1Neurology Service, Walter Reed Army Medical Center, Washington, D.C. 20307-5001.

Movement Disorders : Official Journal of the Movement Disorder Society
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

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Segmental axial dystonia, a rare disorder affecting trunk and neck muscles, can occur after head injury. This case study shows trihexyphenidyl effectively treated dystonia and scoliosis following a brain injury.

Area of Science:

  • Neurology
  • Neuroscience
  • Movement Disorders

Background:

  • Segmental axial dystonia is a rare condition characterized by involuntary muscle contractions in the trunk and neck.
  • The etiology of segmental axial dystonia is often idiopathic, but acquired causes are increasingly recognized.

Observation:

  • A 31-year-old male presented with progressive scoliosis and marked paraspinal muscle dystonia.
  • Symptoms developed six months after sustaining a closed head injury.
  • Neuroimaging revealed three small areas of encephalomalacia, including one in the head of the caudate nucleus.

Findings:

  • The patient's dystonia and scoliosis significantly improved following treatment with trihexyphenidyl.
  • This suggests a potential therapeutic role for anticholinergic medication in acquired axial dystonia.

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Implications:

  • Acquired segmental axial dystonia may result from focal brain injury, particularly affecting the basal ganglia.
  • Early diagnosis and treatment with medications like trihexyphenidyl can lead to substantial recovery.
  • Further research is warranted to explore the neurobiological mechanisms underlying post-traumatic axial dystonia.