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Updated: Aug 20, 2026
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
[Resection of giant pituitary adenomas through transnasal and transsphenoidal approach with nasoendoscope]
Ping Zhang1, Wuyan Lin, Xingqi Yao
1Department of Otolaryngology, Wuhan General Hospital of Guangzhou Military Command, Wuhan, 430070, China.
Objective:
To investigate the feasibility of transnasal and transsphenoidal surgery for giant pituitary adenomas with nasoendoscope.
Method:
The giant pituitary adenomas were resected by the transnasal and transsphenoidal surgery with nasoendoscope in 13 patients.
Result:
The tumors were totally resected in 9 cases (69.2%), subtotally in 3 cases (23.1%) and the resection failed in 1 (7.7%). Vision and visual field were significantly improved in 10 patients (76.9%) one week after the operations, of whom 7 had nearly or completely normal vision and visual field. There were no serious complications or death except transient cerebro spinal fluid leakage in 2 patients.
Conclusion:
It should be noted that the operative manipulation and curative effect of nasoendoscopic surgery on the giant pituitary adenomas may be affected by some factors such as the hemorrhage during the operation, anatomical abnormality, parasellar tissue projecting into the sella, postoperative improper treatment and so on.
