Nonspecific urethritis and reactive arthritis

Nongonococcal urethritis (NGU) is a common sexually transmitted infection most often caused by Chlamydiae and Mycoplasmae. A few other organisms, as well as some nonsexual factors, also contribute to its etiology. NGU can result in considerable physical and psychological morbidity. In a few cases, it can lead to complications like reactive arthritis, and pelvic inflammatory disease, with their attendant morbidities. Correct diagnosis and treatment is therefore imperative in proper management of these cases. While earlier diagnostic support for these infections was limited and expensive, the advent of new methods like the nucleic acid amplification assays (NAA tests) has contributed significantly to better diagnosis. Treatment as per suggested guidelines and follow up of cases and contacts are all crucial in management. Counseling, including advice on behavior change, goes a long way in preventive strategies.