Related Experiment Video
Updated: Aug 20, 2026

Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads
Published on: March 8, 2017
Hidden dynamics of vesicle adhesion induced by specific stickers
Damien Cuvelier1, Pierre Nassoy
1PCC Institut Curie, CNRS UMR 168, 11 rue Pierre et Marie Curie, 75005 Paris, France.
Abstract:
We experimentally studied the adhesion dynamics of vesicles decorated with specific stickers onto bioactive surfaces. The growth laws were found to strongly depend upon the chemical preparation of the substrate and were rationalized with theoretical descriptions based on scaling law arguments. By using a micropipette-free approach, we demonstrate that two-dimensional binding rates between receptor and ligand can be lower than three dimensional on rates by orders of magnitude due to reduced accessibility of the immobilized protein.
Related Concept Videos
Pinching-off of Coated Vesicles
Clathrin Coated Vesicles
Overview of Secretory Vesicles
Various proteins regulate the aggregation of molecules inside the secretory vesicles. Chromogranins...
Fusion of Secretory Vesicles with the Plasma Membrane
In 1993, Jim Rothman proposed that the antiparallel pairing of vesicular and transmembrane SNAREs, or...
Intracellular Signaling Affects Focal Adhesions
Some...
Adherens Junctions
Adherens Junctions are Dynamic
The endothelial cells...

