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Dielectric modulation of biological water

Florin Despa1, Ariel Fernández, R Stephen Berry

  • 1Department of Chemistry, The University of Chicago, Chicago, Illinois 60637, USA.

Physical Review Letters
|December 17, 2004
PubMed

Abstract:

We show that water constrained by vicinal hydrophobes undergoes a librational dynamics that lowers the dielectric susceptibility and induces a "redshift" of the relaxation frequency in the hydration shell. The results shed light on the way proteins enhance their intramolecular interactions as they fold or associate.

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