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FlyBase: genes and gene models.

Rachel A Drysdale1, Madeline A Crosby,

  • 1Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK. rd120@gen.cam.ac.uk

Nucleic Acids Research
|December 21, 2004
PubMed
Summary
This summary is machine-generated.

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FlyBase is a key resource for Drosophilidae insect genetic and molecular data. It offers integrated data for Drosophila melanogaster and is expanding to include more Drosophila species with new genomic sequences.

Area of Science:

  • Genomics
  • Bioinformatics
  • Entomology

Background:

  • FlyBase is the principal database for genetic and molecular information on the Drosophilidae family.
  • It provides comprehensive, integrated data for Drosophila melanogaster, the most studied species.

Purpose of the Study:

  • To describe the scope and content of the FlyBase database.
  • To highlight the expansion of data to include additional Drosophila species.

Main Methods:

  • Data aggregation from various sources.
  • Integration of diverse data types including phenotypes, genetic maps, and molecular functions.
  • Development of sequence-level gene models and functional classifications.

Main Results:

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  • FlyBase offers extensive genetic and molecular data for Drosophila melanogaster.
  • Data includes phenotypes, allele characterization, cytological maps, expression patterns, anatomical images, transgenic information, gene models, and functional classifications.
  • Data for other Drosophila species is increasing and will expand with new genomic sequences.

    • Conclusions:

    • FlyBase serves as an essential integrated resource for Drosophilidae research.
    • The database is expanding its coverage to encompass a wider range of Drosophila species, enhancing its utility for comparative genomics and evolutionary studies.