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Updated: Aug 12, 2026

High-throughput Detection Method for Influenza Virus
10:05

High-throughput Detection Method for Influenza Virus

Published on: February 4, 2012

[Discovery of a novel reassortant H1N2 influenza virus]

Y Guo1, J Qi, M Wang

  • 1Institute of Virology, Chinese Academy of Preventive Medicine, Beijing 100052.

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi = Zhonghua Shiyan He Linchuang Bingduxue Zazhi = Chinese Journal of Experimental and Clinical Virology
|June 1, 1997
PubMed

Insights

Three novel reassortant H1N2 influenza A virus strains were identified in Taiyuan in 1996. These findings highlight the potential for new influenza virus subtypes to emerge and circulate in human populations.

Area of Science:

  • Virology
  • Epidemiology
  • Molecular Biology

Context:

  • Influenza A virus surveillance is crucial for public health.
  • Understanding influenza virus evolution aids in predicting and preventing outbreaks.
  • Previous influenza A virus strains (H1N1, H3N2) circulated in human populations.

Purpose:

  • To identify and characterize influenza A virus strains isolated from patients with influenza-like illness.
  • To determine the subtype and genetic makeup of novel influenza A virus isolates.
  • To investigate the potential for reassortment in influenza A virus evolution.

Summary:

  • Three influenza A virus strains were isolated from patients in Taiyuan in January 1996.
  • Serological analysis indicated the isolates were a novel H1N2 subtype, distinct from previously identified H1N2 and recent H1N1 strains.
  • RNA segment analysis revealed genetic similarities to both A/PR/8/34 (H1N1) and A/Wuhan/359/95 (H3N2) viruses, confirming a reassortant nature.

Impact:

  • Identified a novel reassortant H1N2 influenza A virus, expanding knowledge of influenza diversity.
  • Provides insights into the mechanisms of influenza virus genetic reassortment.
  • Contributes to ongoing influenza surveillance and pandemic preparedness efforts.

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