[Absence epilepsy. A review of our 14 years' experience]

T Ureña-Hornos1, R Rubio-Rubio, D Gros-Esteban

  • 1Servicio de Neuropediatría, Hospital Universitario Miguel Servet, Zaragoza, Spain.

Revista De Neurologia
|December 31, 2004
PubMed

Insights

Absence epilepsy (AE) in children is typically diagnosed and treated effectively, with most patients achieving remission. Early expert management and attention to associated learning issues are crucial for long-term outcomes.

Area of Science:

  • Pediatric Neurology
  • Epileptology
  • Clinical Neuroscience

Context:

  • Absence epilepsy (AE) is a common childhood epilepsy characterized by brief episodes of impaired consciousness and generalized spike-wave discharges on EEG.
  • Effective management strategies are essential to prevent long-term neurological and developmental consequences.

Purpose:

  • To evaluate the long-term outcomes and treatment response in a cohort of children diagnosed with absence epilepsy.
  • To identify factors associated with successful remission and persistent symptoms.

Summary:

  • This study reviewed 49 pediatric cases of absence epilepsy, identifying a 10% prevalence within a larger epilepsy cohort.
  • Most children achieved remission, with 42 out of 49 being seizure-free for over six months, including 21 off medication.
  • Two females on treatment remained the only ones with ongoing absences, highlighting treatment efficacy.

Impact:

  • Absence epilepsy is generally manageable with appropriate treatment, often responding to monotherapy or combination antiepileptic drugs.
  • Prompt diagnosis and expert management by neurologists are key to achieving sustained seizure control.
  • Associated psychosocial and learning difficulties in children with AE necessitate comprehensive, multidisciplinary care.
Abstract

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